Interestingly, we had previously shown that a number of isolates of C. jejuni from human enteritis patients induced colitis in IL-10−/− mice whereas isolates from human GBS patients colonized the IL-10−/− mice but did not induce colitis.19 We also showed that the C. jejuni induced colitis response depended on an upregulated Type 1 (interferon, IFN-γ) and Type17 (IL-17) cytokine response in the colon. Here, IL10 is linked to colitis.