We have also previously shown that the colitogenic isolate C. jejuni 11168 colonizes IL-10+/+ mice asymptomatically.33 However, the infected IL-10+/+ mice exhibit anti-Campylobacter antibodies of the same classes (IgG2b, IgG2c and IgG3) as the IL-10−/− mice.20 Therefore, we aimed to determine if IL-10 affects autoantibody production during infection with a GBS isolate. The gene discussed is IGHG3; the disease is infection.