CRP and autoimmune disease: A significant difference (p < 0.05) was observed in the incidence rate of TRAEs among patients stratified by age (< 65 years [44.3%] vs ≥ 65 years [53.5%]; < 75 years [47.6%] vs ≥ 75 years [61.0%]); CRP levels (< 5 mg/dL [53.8%] vs ≥ 5 mg/dL [43.8%]); and past medical history (presence [54.5%] vs absence [39.4%]), including hepatic diseases (65.9% vs 48.0%), thyroid diseases (58.0% vs 46.8%), and autoimmune diseases (75.0% vs 48.8%; Table 3).