HIF1A and renal fibrosis: To further investigate the possible molecular mechanism by which ablation of TIGAR exacerbates Ang‐II‐induced renal fibrosis and injury, we examined the expression of glycolytic enzymes, hypoxia‐inducible factor‐1 alpha (HIF‐1α), and transforming growth factor beta 1 (TGF‐β1), which play a critical role during the development of renal fibrosis and injury.