Overall, age over 65 years, HR 3.27 [2.83, 3.77], p < .0001 (Figure S3A),58, 157, 172 HbA1C over 70 mmol, HR 2.75 [2.60, 2.91] p < .0001 (Figure S3C), insulin use HR 2.80 [2.29, 3.44], p < .0001 (Figure S3E), were found to increase the risk of mortality amongst patients with diabetes. Here, INS is linked to diabetes mellitus.