Differential expression analysis showed that compared with the low-inflammatory response group, the high-inflammatory response group had higher expression levels of most pro-inflammatory genes such as CCL2, CCL3, CCL4, TNF-α, IFN-γ, IL-6 and anti-inflammatory genes such as IL-10, TGF-β, indicating an active inflammatory response of AML cells (Figure 2E). Here, TNF is linked to acute myeloid leukemia.