T2DM nearly doubles the risk of coronary heart disease (CHD) and stroke, and correlates with worse prognosis and increased cardiovascular disease (CVD) mortality.1 The impact of T2DM on CVD is partly mediated through diabetic dyslipidaemia, characterised by low high-density lipoprotein (HDL), hypertriglyceridaemia, and increased Apo-B levels. The gene discussed is APOB; the disease is type 2 diabetes mellitus.