Importantly, p‐XPO5 was downregulated, whereas miR‐122 and miR‐200b were elevated in SK‐Hep1 B55β tumor (Figure 6C and D), indicating that B55β exerts in vivo anti‐HCC role through dephosphorylating XPO5 and promoting some miRNA expression. Here, XPO5 is linked to hepatocellular carcinoma.