DARP EC1 binds to the EpCAM receptor with a picomolar affinity (Kd = 68 pM).EpCAM, a transmembrane glycoprotein with a molecular weight of 40 kDa andconsisting of 314 amino acid residues, was first discovered as a tumor antigenin colon cancer cells in 1979. Here, EPCAM is linked to neoplasm.