GATA2 and immunodeficiency disease: Of note, heterozygotes harboring the latter GATA2 gene mutations were found to exhibit features of various types of hematovascular-associated immunodeficiencies, such as Emberger syndrome, which displays primary lymphedema25; dendritic cell, monocyte B, and NK lymphoid (DCML) deficiency, which is characterized by decreases in circulating B cells (BCs), natural killer cells (NKCs), dendritic cells (DCs), and monocytes26; and MonoMAC syndrome, which is defined as DCML deficiency accompanying Mycobacterium avium complex infection27.