Amongst the immunostimulators, CD276, CD40, CD48, CD86, IL6, MICB, TMEM173 and TNFRSF8 presented the highest correlation coefficients in LGG, whereas TNFRSF25, IL6R displayed the highest correlation coefficients in GBM (Supplementary Fig. S10). The gene discussed is IL6R; the disease is glioblastoma.