GPX7 and neoplasm: These results are in accordance with the finding of gene ontology terms for GPX7-co-expressed genes being related to stromal reactions (e.g.: immune cell infiltration and IFN-I response) in LGG, but being mainly related to metabolic processes in GBM, suggesting that while in LGG GPX7 activation directly impacts the tumor microenvironment, in GBM the affected processes are tumor-cell intrinsic.