Here, we found that GPX7 was negatively associated with the tumor purity in LGG (ρ = − 0.486; p = 8.63e−30) (Fig. 10 and Supplementary Table S7) but positively correlated to it in GBM (ρ = 0.311; p = 2.02e−04) (Fig. 11 and Supplementary Table S7). This evidence concerns the gene GPX7 and neoplasm.