GPX7 and colon adenocarcinoma: Lastly, another potential insight into the epigenetic mechanisms related to GPX7 expression comes from our co-expression analyses showing that specific miRNA signatures can regulate GPX7 in gliomas, concurrent with a previous report wherein miR-137 and miR-29b were shown to bind to the 3′ UTR region of GPX7 and inhibit its expression in both SW480 (human colon adenocarcinoma) and HEK293 (human embryonic kidney cell line) cell lines140.