Upon identifying these miRNAs signatures in both cohorts, we focused on the gene-miRNA interactions with a primary focus on predicting the miRNAs that potentially interact with GPX7. A total of 8 miRNAs (hsa-mir-29c-3p; hsa-mir-137-3p; hsa-mir-767-5p; hsa-miR-196a-5p; hsa-miR-196b-5p; hsa-miR-92b-5p, hsa-miR-885-3p and hsa-miR-139-3p) were identified for LGG and 3 miRNAs (hsa-miR-29c-3p, hsa-let-7e-5p, hsa-miR-29b-3p) were identified for GBM. This evidence concerns the gene GPX7 and glioblastoma.