Of the remaining non-BRAFV600E cases, including the MN1-rearranged tumor lacking MN1-BEND2 (C16), three grouped with the nonspecific “low-grade glioma/supratentorial pilocytic astrocytoma/ganglioglioma” methylation class6, and C1 containing the ZFTA-RELA fusion, grouped with RELA ependymomas. Here, RELA is linked to central nervous system cancer.