Oxygen consumption rates (OCR) were functionally assessed by Seahorse in primary AML cells, indicating that OCR was significantly higher in FLT3-ITD+ AMLs compared to FLT3-wt AMLs (Fig. 1d), which correlated with SUCLG2 or SDHB expression (Fig. 1e). The gene discussed is SDHB; the disease is acute myeloid leukemia.