Next, we independently confirmed these data using the MILE AML transcriptome dataset (GSE13159) and healthy HSPCs (GSE42519) and observed that indeed the inv16 and MLL-rearranged AML subtypes express significantly higher levels of SUCLG2 compared to other AML subgroups (Supplementary Fig. 1f). Here, KMT2A is linked to acute myeloid leukemia.