FLT3 and acute myeloid leukemia: Although BM AML chimerism after 3-NPA treatment was comparable to controls in both HL60 and MV4–11 transplanted mice, in contrast, 3-NPA treatment decreased disease burden in peripheral blood and resulted in a reduced spleen size in OXPHOS-dependent FLT3-ITD+ MV4–11 cells (Fig. 5k–m).