Despite the expression of AXIN2 in many tissues (Supplementary Fig. 2a), we found that rs143348853 is a significant AXIN2 eQTL only in Epstein Barr Virus (EBV)-transformed lymphocytes, whole blood and spleen (GTEx portal, Fig. 2a), and primary lymph-CLL tumors (PCAWG, Fig. 2a, b). Here, AXIN2 is linked to B-cell chronic lymphocytic leukemia.