Consistently, CPTAC-GP1 was significantly associated with poorer survival than CPTAC-GP2 and CPTAC-GP3 (log-rank test, p = 0.001, Supplementary Fig. 6c), in line with the survival differences among the three subtypes in the Chinese cohort (Fig. 5b), indicating the robustness of proteomic subtyping based on the Chinese ccRCC cohort. This evidence concerns the gene GP2 and nonpapillary renal cell carcinoma.