In addition, increased NNMT expression in 786-O and ACHN promoted xenograft tumor growth in nude mice, especially in IR-treated cell xenografts, whereas inhibition of K-Hcy by intraperitoneal injection of N-acetyl-cysteine (NAC)56,57 delayed xenograft growth (Fig. 7p, q). The gene discussed is NNMT; the disease is neoplasm.