We proceeded to look at a metabolic gene signature42 and interestingly, SCLC-P samples showed high expression of a subset of metabolic genes in comparison to the non-SCLC-P samples (Fig. 5e) such as ABCB6, PGD, or G6PD. While a clear subset of genes was overexpressed in the MYChi SCLC-P samples, no clear set of metabolic genes was regulated in the MYCNhi or MYCLhi SCLC samples, highlighting some degree of metabolic heterogeneity in our SCLC sample set. Here, ABCB6 is linked to small cell lung carcinoma.