By contrast, suppression of Prdm1, which encodes BLIMP1 and inhibits the differentiation of follicular T helper (TFH) cells after viral infection, resulted in significant enrichment (P < 0.05, Log2-FC > 2) of T cells (Fig. 1B, and Supplementary Fig. 1D). The gene discussed is PRDM1; the disease is viral infectious disease.