Despite a marked difference between the prevalence of CR in the ventricles versus the atria in all patients, no significant difference of CR prevalence in each structure was found when comparing TSC1 vs TSC2 hearts (Fig. 3B), implying that the tumours appear at the same rate in each heart structure no matter the genotype (IVS, z = −0.162, p = 0.873; LV, z = 0.695, p = 0.490; RV, z = 0.969, p = 0.332; LA, z = −1.02, p = 0.308; RA, z = 0.681, p = 0.497). Here, TSC2 is linked to neoplasm.