TESK2 and HIV infectious disease: In addition, several EWAS from the EWAS catalog (http://ewascatalog.org/?cpg=cg0036120) showed the association of hypermethylated CpG in CCDC163P/MMACHC and TESK2 promoters with sex, age, child abuse, rheumatoid arthritis, and five-year Increase in epigenomic biological age of subjects with chronic HIV Infection [34–37].