Moreover, Nie et al. also used AAL to extract serum fucosylated glycoproteins with quantitative proteomics, and found that the combination of AACT, THBS1, and haptoglobin (HPT) could differentiate patients with pancreatic cancer from healthy controls, with an AUC of 0.95 [14]. Here, THBS1 is linked to familial pancreatic carcinoma.