As the data showed that cancer cells with a high copy number of the TAZ gene were sensitive to EGFR/HER2 blockade, we speculated that the EGFR/HER2 signaling pathways may be required for the survival of cancer cells with a high TAZ activity, or possibly that activation of EGFR/HER2 signaling may be required for TAZ-mediated carcinogenesis. This evidence concerns the gene WWTR1 and cancer.