Given the fact that macrophages did not express FGFRs (Figure 3, A and B) and that FGF-2 stimulation did not alter macrophage migration (Supplemental Figure 3, B and C), we hypothesized that FGF-2 indirectly activates macrophages via fibroblasts or pericytes for tumor cell migration. The gene discussed is FGF2; the disease is neoplasm.