Out of 248 (74.92%) highly expressed genes (depth greater than 100 reads in 90% of either control or COVID-19 samples, hypothesizing that high expression would indicate a direct role), we found only 16 genes, including ERGIC1, GGH, PCSK6 and PLOD2, that were differentially expressed only in the G2 group, suggesting no significant over-representation of the human host interactome in our patients (P=0.985 using a hypergeometric test). This evidence concerns the gene PCSK6 and COVID-19.