SOX2 and cancer: The global transcriptional changes observed in the HuMiX experiments, including the activation of Th17 and AhR receptor signalling, but also the induction of cancer stemness genes (for example SOX2), correlated with those observed in tissues from Fusobacteriumhigh patients (Extended Data Fig. 2h,i, see also Fig. 2b in comparison with Extended Data Fig. 1e,g).