Similar to the results in the region-specific analysis, rs3865444 was associated with the ASE of the second exon of CD33 measured at chr19:51728641 (rs2455069) and chr19:51728477 (rs12459419) in monocytes (p = 4.52E-12 and 2.05E-6) (Fig. 6a), confirming that this AD-associated SNP is an sQTL of exon 2 reported in [46]. This evidence concerns the gene CD33 and Alzheimer disease.