The association between intolerance and OSw/oS remained significant (adjusted HR 9.50, 95% CI 5.25–17.20, p < 0.001), even after adjustment for potential confounders, such as sex, log transformed-age in months, bronchial asthma, allergic rhinitis, history of anaphylaxis, allergic symptoms with low-dose OFC, log transformed-specific IgE titers, and the type of food allergen (Table 4). This evidence concerns the gene IGHE and allergic rhinitis.