INS and type 2 diabetes mellitus: Comparing the results of this study with the above studies, it showed that the effect of 48 mg/kg/day (VER 48 group) on improving blood glucose in T2DM rats was similar to that of 100 mg/kg/day (treatment group) on improving blood glucose in T2DM mice, both of them significantly reduced blood glucose, which might be caused by the fact that verapamil could promote the survival and function of pancreatic beta cells, and enhance insulin secretion [44].