PTEN and nasopharyngeal carcinoma: It has been shown that EBV-miR-BART1 has a direct effect on the expression of NPC mechanism-associated genes such as phosphoserine aminotransferase 1 (pSAT1), phosphoglycerate dehydrogenase (PHGDH) and phosphatase and tensin homolog (PTEN) [77, 80].