IL1B and arthropathy: We then analyzed the expression levels of selected tissue‐specific marker genes, proinflammatory cytokines, matrix metalloproteinases (MMPs), and other degenerative markers in all four tissues that have been well studied in joint disease‐related investigations (Figure 4c, with the list of genes, p‐values, and adjusted p‐values provided in Table S5, Supporting Information).[12, 13] Upregulated expression of major catabolic genes was detected within the SFT in the IL‐1β‐treated, inflamed miniJoint.