The transcriptional coactivator YAP1 (Yes1 associated transcriptional regulator) and IL6ST (interleukin 6 cytokine family signal transducer)-JAK (Janus kinase) signaling axis have a prominent role in tumor formation and growth, promoting cancer cell survival, proliferation, migration and metastasis [14,15]. This evidence concerns the gene YAP1 and neoplasm.