NLRP3, as an important member of the inflammatory complex family, monitors danger signals in the cytoplasm, identifies various pathogenic microorganisms and their metabolites, regulates the immune response, causes inflammatory responses [32], enhances the proliferation, invasion and anti-apoptotic ability of tumour cells, and reduces the sensitivity of tumour cells to chemotherapy drugs [33]. This evidence concerns the gene NLRP3 and neoplasm.