We adopted the real‐time in vivo fluorescence imaging technique to detect and track the distribution and retention of MTem‐Rho on the eyes of dry eye model mice.[50, 51] As shown in Figure 4h, the MTem‐Rho group had almost the same fluorescence intensity as the Rho group after administration for the first 30 s. The gene discussed is RHO; the disease is dry eye syndrome.