The elevation of MMP‐9 is vitally and closely related to dry eye syndrome, and its detection has been utilized as a novel means in the diagnosis of DED.[59] The powerful MMP‐9 elimination in MTem/Los group explains why the minimum damage occurred in corneal epithelial cells (Figure 5b) with the fewest green spots observed under the slit lamp (Figure 4b). This evidence concerns the gene MMP9 and dry eye syndrome.