Among the two immunological parameters, namely PGE2 and IL1-ß, that were measured in saliva samples (Figures 4B,C), PGE2 did not change at any time in any of the groups, while IL1-ß significantly increased during the experimental gingivitis phase only in the group B (p < 0.0001, Friedman Test). Here, IL1B is linked to gingivitis.