The transient short-term occlusion with rapid tissue reperfusion shortly after embolization obtained via DSMs-TACE has been considered likely to reduce hypoxia-dependent VEGF over production, and thus reduce the risk of rebound neovascularization, tumor re-growth and recurrence [5, 9, 10, 11, 12, 13, 14]. The gene discussed is VEGFA; the disease is neoplasm.