CYCS and non-small cell lung carcinoma: The exogenous expression of MBP1 in NSCLC cells inhibits cell proliferation and induces mitochondrial pore formation, which does not allow accumulation of cytochrome c. MBP1 can also induce necrosis-like cell death with more mitochondrial permeability transition in human NSCLC cells (H1299); therefore, MBP1 could be a useful therapeutic intervention tool against NSCLC tumor growth.66