CKAP5 and rhabdomyosarcoma: We demonstrated that preventing the circZNF609/CKAP5 mRNA interaction, through either small interfering RNAs (siRNAs) against circZNF609 or locked nucleic acid (LNA)-modified oligonucleotides against the pairing region, sensitizes rhabdomyosarcoma cells to microtubule-targeting chemotherapeutic agents.