While miR-155 directly targeted histone deacetylase 4 (HDAC4), a corepressor partner of BCL6, and ectopic expression of HDAC4 reduced miR-155-induced proliferation and clonogenic potential, simultaneously increased apoptosis in human-activated B cell-type that diffuse large B cell lymphoma (DLBCL) cells [73]. This evidence concerns the gene HDAC4 and diffuse large B-cell lymphoma.