In addition, a study by Hatton et al. [83] found that EBV latent membrane protein 1 (LMP1) regulated miR-155 and its targeted-FOXO3a in B cells by activating PI3K p110α, which could be a reasonable therapeutic target and biomarker for EBV+ B cell lymphoma. This evidence concerns the gene FOXO3 and B-cell non-Hodgkin lymphoma.