A plasma phospholipid transfer protein knockout (PLTPO) experiment further pointed out that in patients who have undergone PCI treatment, the severity of diabetes may be positively correlated with cardiovascular death because the risk of cardiovascular death was 50% higher in patients with diabetes who received insulin treatment than in those who did not; moreover, the prognosis is worse after normal blood flow is restored by stent placement [67]. The gene discussed is PLTP; the disease is diabetes mellitus.