Over-expression of CYP2J2 in endothelium was found to improve cardiac function by increasing angiogenesis in MI-induced heart failure (29), whereas over-expression of CYP2J2 by tail vein injection of rAAV9-CYP2J2 was found to attenuate ethanol-induced myocardial dysfunction (30). The gene discussed is CYP2J2; the disease is myocardial infarction.