Advances in HSP60 immune system network suggest that the peptides derived from this protein may also be helping to alleviate the inflammatory TLR4-related effects, as peptides derived from this protein have reported to have anti-inflammatory effects with promising results on autoimmune and cardiovascular diseases, which are pathologies where TLR4 also represents a key role (18, 19, 59, 60). The gene discussed is TLR4; the disease is cardiovascular disorder.