Moreover, it is important that the result of our study identifies that NT-proBNP may play a useful role in risk stratification of adult patients with acute myocarditis, independently of other currently used tools including echocardiography and electrocardiogram, and NT-proBNP more than 7,204 pg/mL might be a reasonable cut-off value in acute stage for risk stratification. The gene discussed is NPPB; the disease is myocarditis.