NPPB and Tako-tsubo cardiomyopathy: NT-proBNP levels peaked around the same time as the troponins and the peak concentration was within the same range as that of troponin I.<h4>Discussion</h4>Our findings indicate that assaying circulating cardiac biomarkers, especially troponin I and NT-proBNP, may be a useful complement to non-invasive cardiac imaging including transthoracic echocardiography and cardiovascular magnetic resonance imaging, in the diagnosis of Takotsubo syndrome.