For example, mutations of DLG4 (encoding PSD95) are associated with both SCZ and autism, and a missense mutation of DLG4 (T611I) that weakens the PSD95/SAPAP interaction could interfere with synapse development and cause ID (Hahn et al., 2006; Rauch et al., 2012; Hashimoto et al., 2013; Lelieveld et al., 2016). Here, DLG4 is linked to autism.