The downregulated hub genes in IUGR-hypoxia included Cyp2f4, Agtr1a, Eci1, Acsl5, Acat1, Acadl, Lipc, Hadha, Acads, and Acadvl, while the upregulated hub genes in IUGR-hypoxia included Acsm3, Cyp2j4, Mapk14, Cyp2j10, Stard4, Fam126b, and Hacl1. The gene discussed is AGTR1; the disease is fetal growth restriction.