Interestingly, MetaCore analyses highlighted GO terms related to inflammatory/immune response that were only prominent in the MPBCS cohort and not in the TCGA samples; nevertheless, this is not a unique feature of MPBCS, as other more specific immunogenomic analysis of the TCGA database has already associated most Basal and some of HER2+ and LumB breast cancers with an IFN-γ dominant class, with a high content of CD8-T cells and of TCR diversity (53). This evidence concerns the gene ERBB2 and breast cancer.