The data showed that hsa-miR-297 mimic dramatically blunted luciferase activities of the CRC cells transfected with the wild-type GSTA2 reporter gene vector, but not the hsa-miR-297-binding sites of the mutant one (two binding motifs for hsa-miR-297 in 3′-UTR of GSTA2 mRNA were mutated) (Figure 5D). This evidence concerns the gene GSTA2 and colorectal carcinoma.