A total of 1674 downregulated genes and 905 upregulated genes were obtained from the screening of luminal A breast cancer (Figure 2A); from the screening of luminal B breast cancer, 2270 downregulated genes and 1186 upregulated genes were obtained (Figure 2B); and from the screening of HER2-enriched breast cancer, 2513 downregulated genes and 974 upregulated genes were obtained (Figure 2C). Here, ERBB2 is linked to breast cancer.