Among the kinase DEPs in the HCC-Gao cohort, 9 showed over 2-fold of up-regulation in tumors, namely, MAPK1 (log2-fold-change [FC] = 1.9, FDR = 7.3e-44), GSK3B (FC = 1.6, FDR = 1.5e-44), RPS6KA3 (FC = 2.1, FDR = 2.3e-32), STK3 (FC = 1.4, FDR = 1. The gene discussed is STK3; the disease is hepatocellular carcinoma.