CD47 and acute myeloid leukemia: By contrast, CD47 in AML tissues was mainly enriched in Hallmark pathways, such as protein secretion, TGF-β signaling, and NOTCH signaling (Figure 5C), and KEGG pathways, such as ribosomes, ubiquitin-mediated protein hydrolysis, and amyl-TRNA biosynthesis (Figure 5D).