S100A9 and cancer: Of these DEPs, other studies reported 70% (93 DEPs) as the colorectal abnormalities at the protein or mRNA level, 16% (21 DEPs) were categorized as the pan-cancer genes (such as LTF, S100A9, and CDK1), 30% (39 DEPs) were identified as secreted proteins (most of which were likely found in the cytoplasm and potentially detectable in body fluid), and 12% (16 DEPs) were regarded as the drug targets.