Interestingly, USP10 expression with increased (OS, HR = 2.41, P = 0.027) or decreased (OS, HR = 2, P = 0.012) CD8+ T cell infiltration had a marked impact on the survival of patients with PAAD and predicted a worse survival outcome (Figure 10A and Supplementary Figure 4A). The gene discussed is CD8A; the disease is pancreatic adenocarcinoma.